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Published: . Dec 2014

Rohatgi S, Jagannathan JP, Rosenthal MH, Kim KW, Ramaiya NH, Krajewski KM

Vascular toxicity associated with chemotherapy and molecular targeted therapy: what should a radiologist know?
(AJR Am J Roentgenol)

Venous and arterial thromboembolic events and rarely hemorrhage are complications of chemotherapy and, more recently, of molecular targeted therapy in patients with solid and hematologic malignancies. This article will use a drug-based approach to illustrate, with examples, vessel damage and end-organ damage induced by molecular targeted therapy and chemotherapy in cancer patients and will provide a clinical perspective. Imaging plays a key role in the detection of complications of cancer therapies. A high index of suspicion and an awareness of modern-day drug toxicities are key to the early diagnosis and management of these complications.

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Read more articles from the authors:
1. Rohatgi S
2. Jagannathan JP
3. Rosenthal MH
4. Kim KW
5. Ramaiya NH
6. Krajewski KM

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